Spectrophotometric determination of quinolone antibiotics by an association complex formation with aluminum(III) and erythrosin.

نویسندگان

  • Takako Yamaguchi
  • Masahiro Nakao
  • Ryosuke Nakahara
  • Yuka Nishioka
  • Chiho Ikeda
  • Yoshikazu Fujita
چکیده

A simple and sensitive spectrophotometric method for the determination of quinolone antibiotics was established based on an association complex formation with aluminum(III) and erythrosin. In the determination of ofloxacin as a quinolone antibiotic, Beer's law is obeyed in the range of 0.1 - 3.2 microg ml(-1), with an effective molar absorptivity at 555 nm and the relative standard deviation being 1.2 x 10(5) L mol(-1) cm(-1) and 0.9% (n = 6). This method was successfully applied to the assay of quinolone antibiotics in pharmaceutical preparations.

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عنوان ژورنال:
  • Analytical sciences : the international journal of the Japan Society for Analytical Chemistry

دوره 25 1  شماره 

صفحات  -

تاریخ انتشار 2009